Takashi Sato, MD, PhD

Takashi Sato

Neural Basis for Motion Induced Sickness in Mice
Takashi Sato, MD, PhD

Medical University of South Carolina

Grant: $50,000

Discovery Grant

This proposal aims to investigate how information about balance is processed in the vestibular nucleus, focusing on neural circuits and information processing. Using advanced imaging techniques, the research will explore how the information is represented in the vestibular nucleus and is transformed in the downstream brain area. Our research will advance understanding of vestibular disorders.

About the Researcher

Takashi Sato, MD, PhD, obtained his medical degree from the University of Tokyo and his Ph.D. from Vanderbilt University. After completing his postdoctoral training at Janelia Research Campus, he served as a Junior Group Leader at the University of Tübingen before joining the Medical University of South Carolina. The research of the Sato Lab focuses on sensory-motor processing in the brain, with an emphasis on eye movements and forepaw movements (e.g., Hasegawa et al., Cell Rep, 2017; Itokazu et al., Nat Commun, 2018). The lab is applying its expertise in imaging techniques and mouse behavior to unravel vestibular information processing.

About the Research

Neural Basis for Motion Induced Sickness in Mice

This research focuses on understanding how the brain processes signals from the inner ear, which plays a crucial role in controlling balance and detecting movement. These signals are vital for stabilizing vision and maintaining posture. Using advanced imaging technology, the study will examine how the brainstem processes signals from head movements and shares them with other parts of the brain. By studying how different
neurons in the brainstem respond to head movements, the research aims to uncover the mechanisms behind balance disorders such as vertigo and motion sickness. Ultimately, this study will provide new insights into how the brain processes balance-related information, with potential implications for improving treatments for balance and motion-related disorders, including motion sickness and Meniere’s disease.

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